It is 100% safe to optimize your table by removing all _transient_ entries. WordPress will generate new entries if requires in the future. Just use below query to optimize your wp_options table. delete from `wp_options` where `option_name` like '_transient_%'

https://crunchify.com/what-are-transient-entries-in-wp-options-table-transient-buildup-information/

delete from `wp_options` where `option_name` like '%_transient_%' 12.05.23

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